Preimplantation Genetic Testing (PGT) is a Screening procedure that identifies chromosomal abnormalities in an embryo.
It is carried out before embryos are transferred to the uterus in In Vitro Fertilisation (IVF). This procedure is also known as IVF Preimplantation Genetic Testing. The testing covers a range of genetic disorders that can lead to miscarriage, implantation failure, and birth defects in IVF-conceived children. This is particularly valuable for detecting common genetic disorders such as Down syndrome, sickle cell anaemia, and others.
Preimplantation Genetic Diagnosis (PGD) involves testing for a specific genetic disorder before the embryo is implanted in the uterus. Various genetic tests can be conducted on the embryo to identify any anomalies.
These tests are used by doctors to assess the suitability of the embryo for implantation. Embryos showing anomalies may result in spontaneous abortions or failed implantations. Preimplantation Genetic Testing (PGT) contributes to improving the success rates of IVF and prevents the need for unsuccessful IVF cycles. Additionally, it helps to spare patients from emotional and physical trauma.
The experienced fertility doctors will discuss the necessity of PGT-A with you during consulting sessions. Based on the DNA evaluation results that reveal whether you and your spouse carry the gene causing the illness, the doctor will determine a clinical diagnosis.
Your recommended genetic counsellor will go through the specifics of the disease, your genetic susceptibility evaluation, and its likelihood to arise during pregnancy. The implications and limitations of PGT, as well as potential results, are discussed during counselling.
After receiving your results and consent, the PGT laboratory will assess if PGT-A is appropriate for your condition. You and your spouse will need to provide blood samples to the testing lab of the clinic after giving permission to prepare for the PGT workup. Your IVF cycle might start when the workup procedures are finished.